First-generation interaction maps of Src homology 2 (SH2) domains with receptor tyrosine kinase (RTK) phosphosites have previously been generated using protein microarray (PM) technologies.Here, we developed a large-scale fluorescence polarization (FP) methodology that was able to characterize interactions between SH2 domains and ErbB receptor phos
Hybrid simulation of shock interaction with highly nonuniform plasmas
The impact of capsule imperfections is one of the challenges in achieving reproducible, high-gain ignition of inertial confinement fusion (ICF).The nonuniformities of capsule Screen Protectors imperfections, which create instability seeds during the shock propagation, may cause significant performance degradation.A systematic study of the propagati
Improving outcomes in patients with melanoma: strategies to ensure an early diagnosis
Rachel K Voss,1 Tessa N Woods,1 Kate D Cromwell,1 Kelly C Nelson,2 Janice N Cormier1 1Department of Surgical Oncology, 2Department of Dermatology, Upcycled Top The University of Texas MD Anderson Cancer Center, Houston, TX, USA Abstract: Patients with thin, low-risk melanomas have an excellent long-term prognosis and higher quality of life than tho
RNA viruses in hymenopteran pollinators: evidence of inter-Taxa virus transmission via pollen and potential impact on non-Apis hymenopteran species.
Although overall pollinator populations have Nursery Decoration declined over the last couple of decades, the honey bee (Apis mellifera) malady, colony collapse disorder (CCD), has caused major concern in the agricultural community.Among honey bee pathogens, RNA viruses are emerging as a serious threat and are suspected as major contributors to CCD